ECPI Anatomy and Physiology Exam 1 Practice Test 2026 – Complete Prep Guide

Steroid hormones are derived from cholesterol and produced by the adrenal cortex. The cortex makes corticosteroids like aldosterone and cortisol, as well as adrenal androgens, all of which are steroid hormones. Their lipid-soluble nature lets them diffuse through cell membranes and bind to intracellular receptors, changing gene expression and producing longer-lasting, body-wide effects. This differentiates them from amine and peptide hormones, which are typically water-soluble, bind to receptors on the cell surface, and trigger rapid signaling pathways.